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Innate immunity limits protective adaptive immune responses against pre-erythrocytic malaria parasites
Immunization with attenuated whole Plasmodium sporozoites constitutes a promising vaccination strategy. Compared to replication-deficient parasites, immunization with replication-competent parasites confers better protection and also induces a type I IFN (IFN-1) response, but whether this IFN-1 resp...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718385/ https://ncbi.nlm.nih.gov/pubmed/31477704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11819-0 |
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