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Quantitation of Apurinic/Apyrimidinic Sites in Isolated DNA and in Mammalian Tissue with Reduced Artifact
The apurinic/apyrimidinic (AP) site is a common lesion of DNA damage. The levels of AP sites reported in the literature range widely, which is primarily due to the artefactual generation or loss of AP sites during processing of the DNA. Herein, we have developed a method to quantitate AP sites with...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718090/ https://ncbi.nlm.nih.gov/pubmed/31055913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01351 |
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