Clinical Pharmacokinetics of Sulfobutylether‐β‐Cyclodextrin in Patients With Varying Degrees of Renal Impairment

Delafloxacin, a fluoroquinolone, has activity against Gram‐positive organisms including methicillin‐resistant S aureus and fluoroquinolone‐susceptible and ‐resistant Gram‐negative organisms. The intravenous formulation of delafloxacin contains the excipient sulfobutylether‐β‐cyclodextrin (SBECD), wh...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Hoover, Randall K., Alcorn, Harry, Lawrence, Laura, Paulson, Susan K., Quintas, Megan, Luke, David R., Cammarata, Sue K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Special Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718009/
https://ncbi.nlm.nih.gov/pubmed/29578585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1077
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