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MPRAnalyze: statistical framework for massively parallel reporter assays

Massively parallel reporter assays (MPRAs) can measure the regulatory function of thousands of DNA sequences in a single experiment. Despite growing popularity, MPRA studies are limited by a lack of a unified framework for analyzing the resulting data. Here we present MPRAnalyze: a statistical frame...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Ashuach, Tal, Fischer, David S., Kreimer, Anat, Ahituv, Nadav, Theis, Fabian J., Yosef, Nir
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717970/
https://ncbi.nlm.nih.gov/pubmed/31477158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1787-z
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