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MPRAnalyze: statistical framework for massively parallel reporter assays

Massively parallel reporter assays (MPRAs) can measure the regulatory function of thousands of DNA sequences in a single experiment. Despite growing popularity, MPRA studies are limited by a lack of a unified framework for analyzing the resulting data. Here we present MPRAnalyze: a statistical frame...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Ashuach, Tal, Fischer, David S., Kreimer, Anat, Ahituv, Nadav, Theis, Fabian J., Yosef, Nir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717970/
https://ncbi.nlm.nih.gov/pubmed/31477158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1787-z
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