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Choroid plexus‐derived miR‐204 regulates the number of quiescent neural stem cells in the adult brain

Regulation of adult neural stem cell (NSC) number is critical for lifelong neurogenesis. Here, we identified a post‐transcriptional control mechanism, centered around the microRNA 204 (miR‐204), to control the maintenance of quiescent (q)NSCs. miR‐204 regulates a spectrum of transcripts involved in...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lepko, Tjasa, Pusch, Melanie, Müller, Tamara, Schulte, Dorothea, Ehses, Janina, Kiebler, Michael, Hasler, Julia, Huttner, Hagen B, Vandenbroucke, Roosmarijn E, Vandendriessche, Charysse, Modic, Miha, Martin‐Villalba, Ana, Zhao, Sheng, LLorens‐Bobadilla, Enric, Schneider, Anja, Fischer, Andre, Breunig, Christopher T, Stricker, Stefan H, Götz, Magdalena, Ninkovic, Jovica
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717894/
https://ncbi.nlm.nih.gov/pubmed/31304985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100481
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