Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition

Decreased nitric oxide (NO) bioavailability and oxidative stress are hallmarks of endothelial dysfunction and cardiovascular diseases. Although numerous proteins are S‐nitrosated, whether and how changes in protein S‐nitrosation influence endothelial function under pathophysiological conditions rema...

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Bibliographic Details
Published in:EMBO J
Main Authors: Siragusa, Mauro, Thöle, Janina, Bibli, Sofia‐Iris, Luck, Bert, Loot, Annemarieke E, de Silva, Kevin, Wittig, Ilka, Heidler, Juliana, Stingl, Heike, Randriamboavonjy, Voahanginirina, Kohlstedt, Karin, Brüne, Bernhard, Weigert, Andreas, Fisslthaler, Beate, Fleming, Ingrid
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717893/
https://ncbi.nlm.nih.gov/pubmed/31328803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100938
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