Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation

Humanin (HN) is a mitochondrial peptide that exhibits cytoprotective actions against various stresses and diseases. HN has been shown to induce the phosphorylation of AMP-activated protein kinase (AMPK), which is a negative regulator of receptor activator of nuclear factor-κB ligand (RANKL). However...

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Bibliographic Details
Published in:Korean J Physiol Pharmacol
Main Authors: Kang, Namju, Kim, Ki Woo, Shin, Dong Min
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717796/
https://ncbi.nlm.nih.gov/pubmed/31496878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2019.23.5.411
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