Targeting of DDR1 with antibody‐drug conjugates has antitumor effects in a mouse model of colon carcinoma

DDR1 has been identified as a cancer‐associated receptor tyrosine kinase that is highly expressed in several malignancies relative to normal tissues. Clinically approved multi‐kinase inhibitors, such as nilotinib, inhibit DDR1‐mediated tumor growth in xenograft models, suggesting DDR1 might be a pot...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Tao, Yiran, Wang, Ruixue, Lai, Qinhuai, Wu, Mengdan, Wang, Yuxi, Jiang, Xiaohua, Zeng, Lishi, Zhou, Shijie, Li, Zhongping, Yang, Tinghan, Yao, Yuqin, Wu, Yangping, Yu, Lin, Fu, Yuyin, Lai, Weirong, Peng, Yujia, Lu, Ying, Zhang, Zhixiong, Guo, Cuiyu, Zhang, Guangbing, Gou, Lantu, Yang, Jinliang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717758/
https://ncbi.nlm.nih.gov/pubmed/31116512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12520
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