The effect of cysteine oxidation on DJ-1 cytoprotective function in human alveolar type II cells

DJ-1 is a multifunctional protein with cytoprotective functions. It is localized in the cytoplasm, nucleus, and mitochondria. The conserved cysteine residue at position 106 (Cys106) within DJ-1 serves as a sensor of redox state and can be oxidized to both the sulfinate (-SO(2)(−)) and sulfonate (-SO...

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Udgivet i:Cell Death Dis
Main Authors: Bahmed, Karim, Boukhenouna, Samia, Karim, Loukmane, Andrews, Tessa, Lin, Jiusheng, Powers, Robert, Wilson, Mark A., Lin, Chih-Ru, Messier, Elise, Reisdorph, Nichole, Powell, Roger L., Tang, Hsin-Yao, Mason, Robert J., Criner, Gerard J., Kosmider, Beata
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717737/
https://ncbi.nlm.nih.gov/pubmed/31474749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1833-5
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