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Therapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing in Lung Adenocarcinoma

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) plays an important role in lung cancer progression. Here, we examined the therapeutic efficacy of CEACAM6 gene silencing using an siRNA delivery platform targeting the acidic tumour microenvironment in a lung adenocarcinoma xenograf...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Son, Seung-Myoung, Yun, Jieun, Lee, Sung-Hoon, Han, Hye Sook, Lim, Young Hyun, Woo, Chang Gok, Lee, Ho-Chang, Song, Hyung Geun, Gu, Young-Mi, Lee, Hyun-Jun, Lee, Ok-Jun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717735/
https://ncbi.nlm.nih.gov/pubmed/31474761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48104-5
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