Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [(11)C]PBR28 HRRT PET study

PURPOSE: The purpose of this study was to investigate the effects of ageing, sex and body mass index (BMI) on translocator protein (TSPO) availability in healthy subjects using positron emission tomography (PET) and the radioligand [(11)C]PBR28. METHODS: [(11)C]PBR28 data from 140 healthy volunteers...

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Detalhes bibliográficos
Publicado no:Eur J Nucl Med Mol Imaging
Main Authors: Tuisku, Jouni, Plavén-Sigray, Pontus, Gaiser, Edward C., Airas, Laura, Al-Abdulrasul, Haidar, Brück, Anna, Carson, Richard E., Chen, Ming-Kai, Cosgrove, Kelly P., Ekblad, Laura, Esterlis, Irina, Farde, Lars, Forsberg, Anton, Halldin, Christer, Helin, Semi, Kosek, Eva, Lekander, Mats, Lindgren, Noora, Marjamäki, Päivi, Rissanen, Eero, Sucksdorff, Marcus, Varrone, Andrea, Collste, Karin, Gallezot, Jean-Dominique, Hillmer, Ansel, Huang, Yiyun, Höglund, Caroline O., Johansson, Jarkko, Jucaite, Aurelija, Lampa, Jon, Nabulsi, Nabeel, Pittman, Brian, Sandiego, Christine M., Stenkrona, Per, Rinne, Juha, Matuskey, David, Cervenka, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717599/
https://ncbi.nlm.nih.gov/pubmed/31363804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-019-04403-7
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