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New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia

Genetic iron-overload disorders, mainly hereditary hemochromatosis and untransfused β-thalassemia, affect a large population worldwide. The primary etiology of iron overload in these diseases is insufficient production of hepcidin by the liver, leading to excessive intestinal iron absorption and iro...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Liu, Jing, Liu, Wei, Liu, Yin, Miao, Yang, Guo, Yifan, Song, Haoyang, Wang, Fudi, Zhou, Hongyu, Ganz, Tomas, Yan, Bing, Liu, Sijin
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717595/
https://ncbi.nlm.nih.gov/pubmed/30792208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.209874
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