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Transcriptomic and functional analyses of 3D placental extravillous trophoblast spheroids

Placental extravillous trophoblast (EVT) invasion is essential in establishing proper blood supply to the fetus during pregnancy. However, traditional 2D in vitro systems do not model the in vivo invasion process in an anatomically-relevant manner. Our objectives were to develop a 3D spheroid model...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wong, Michael K., Wahed, Mishquatul, Shawky, Sarah A., Dvorkin-Gheva, Anna, Raha, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717201/
https://ncbi.nlm.nih.gov/pubmed/31471547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48816-8
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