Promoter Hypomethylation of Maspin Inhibits Migration and Invasion of Extravillous Trophoblast Cells during Placentation

OBJECTIVE: Extravillous trophoblast (EVT) cells invade the endometrium and the maternal spiral arterioles during the first trimester. Mammary Serine Protease Inhibitor (Maspin, SERPINB5) plays a putative role in regulating the invasive activity of cytotrophoblasts. The maspin gene is silenced in var...

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Veröffentlicht in:PLoS One
Hauptverfasser: Shi, Xinwei, Liu, Hao, Cao, Jing, Liu, Qing, Tang, Guiju, Liu, Wanlu, Liu, Haiyi, Deng, Dongrui, Qiao, Fuyuan, Wu, Yuanyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532475/
https://ncbi.nlm.nih.gov/pubmed/26263377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135359
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