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Reduced deformability contributes to impaired deoxygenation-induced ATP release from red blood cells of older adult humans
Red blood cells (RBCs) release ATP in response to haemoglobin deoxygenation, which binds to endothelial purinergic receptors and stimulates vasodilatation. This ATP release is impaired in RBCs from older vs. young adults, but the underlying mechanisms are unknown. Using isolated RBCs from young (24±...
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| Publicado no: | J Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6717025/ https://ncbi.nlm.nih.gov/pubmed/31310005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP278338 |
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