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Dissecting the role of hyaluronan synthases in the tumor microenvironment

The tumor microenvironment is becoming a crucial factor in determining the aggressiveness of neoplastic cells. The glycosaminoglycan hyaluronan is one of the principal constituents of both the tumor stroma and the cancer cell surfaces, and its accumulation can dramatically influence patient survival...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:FEBS J
Hauptverfasser: Passi, Alberto, Vigetti, Davide, Buraschi, Simone, Iozzo, Renato V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716524/
https://ncbi.nlm.nih.gov/pubmed/30974514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14847
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