Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

[Image: see text] The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions. To emulate such distinct surface patterns on macromolecules, we used rigid spherical synthetic dendrimers (polyphe...

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Опубликовано в: :ACS Nano
Главные авторы: Wu, Yuzhou, Li, Longjie, Frank, Larissa, Wagner, Jessica, Andreozzi, Patrizia, Hammer, Brenton, D’Alicarnasso, Marco, Pelliccia, Maria, Liu, Weina, Chakrabortty, Sabyasachi, Krol, Silke, Simon, Johanna, Landfester, Katharina, Kuan, Seah Ling, Stellacci, Francesco, Müllen, Klaus, Kreppel, Florian, Weil, Tanja
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716120/
https://ncbi.nlm.nih.gov/pubmed/31322856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b01484
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