Enhanced ATP release and CD73‐mediated adenosine formation sustain adenosine A(2A) receptor over‐activation in a rat model of Parkinson's disease

BACKGROUND AND PURPOSE: Parkinson's disease (PD) involves an initial loss of striatal dopamine terminals evolving into degeneration of dopamine neurons in substantia nigra (SN), which can be modelled by 6‐hydroxydopamine (6‐OHDA) administration. Adenosine A(2A) receptor blockade attenuates PD f...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Pharmacol
Egile Nagusiak: Carmo, Marta, Gonçalves, Francisco Q., Canas, Paula M., Oses, Jean‐Pierre, Fernandes, Francisco D., Duarte, Filipe V., Palmeira, Carlos M., Tomé, Angelo R., Agostinho, Paula, Andrade, Geanne M., Cunha, Rodrigo A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715785/
https://ncbi.nlm.nih.gov/pubmed/31220343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14771
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