Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination

Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system, and have the capacity to regenerate oligodendrocytes and myelin. However, in inflammatory diseases such as multiple sclerosis (MS) remyelination is often incomplete. To investigate how neuroinflammation influenc...

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Pubblicato in:Nat Commun
Autori principali: Kirby, Leslie, Jin, Jing, Cardona, Jaime Gonzalez, Smith, Matthew D., Martin, Kyle A., Wang, Jingya, Strasburger, Hayley, Herbst, Leyla, Alexis, Maya, Karnell, Jodi, Davidson, Todd, Dutta, Ranjan, Goverman, Joan, Bergles, Dwight, Calabresi, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715717/
https://ncbi.nlm.nih.gov/pubmed/31467299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11638-3
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