Alteration of synaptic connectivity of oligodendrocyte precursor cells following demyelination

Oligodendrocyte precursor cells (OPCs) are a major source of remyelinating oligodendrocytes in demyelinating diseases such as Multiple Sclerosis (MS). While OPCs are innervated by unmyelinated axons in the normal brain, the fate of such synaptic contacts after demyelination is still unclear. By comb...

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Pubblicato in:Front Cell Neurosci
Autori principali: Sahel, Aurélia, Ortiz, Fernando C., Kerninon, Christophe, Maldonado, Paloma P., Angulo, María Cecilia, Nait-Oumesmar, Brahim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362325/
https://ncbi.nlm.nih.gov/pubmed/25852473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00077
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