Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may result from fungal induced release of mast cell de...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Botschuijver, Sara, van Diest, Sophie A., van Thiel, Isabelle A. M., Saia, Rafael S., Strik, Anne S., Yu, Zhumei, Maria-Ferreira, Daniele, Welting, Olaf, Keszthelyi, Daniel, Jennings, Gary, Heinsbroek, Sigrid E. M., Elferink, Ronald P. Oude, Schuren, Frank H. J., de Jonge, Wouter J., van den Wijngaard, René M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715706/
https://ncbi.nlm.nih.gov/pubmed/31467355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49096-y
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