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Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease. Here, we investigate whether pharmacological manipulation of the str...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Gonçalves, Ana Cláudia, Towers, Emily R., Haq, Naila, Porco, John A., Pelletier, Jerry, Dawson, Sally J., Gale, Jonathan E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715625/
https://ncbi.nlm.nih.gov/pubmed/31467369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48393-w
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