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Caprin-1 is a target of the deafness gene Pou4f3 and is recruited to stress granules in cochlear hair cells in response to ototoxic damage

The POU4 family of transcription factors are required for survival of specific cell types in different sensory systems. Pou4f3 is essential for the survival of auditory sensory hair cells and several mutations in human POU4F3 cause hearing loss. Thus, genes regulated by Pou4f3 are likely to be essen...

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Detalhes bibliográficos
Main Authors: Towers, Emily R., Kelly, John J., Sud, Richa, Gale, Jonathan E., Dawson, Sally J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056607/
https://ncbi.nlm.nih.gov/pubmed/21402877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076141
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