Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

Organisms must respond to hypoxia to preserve oxygen homeostasis. We identify a thiol oxidase, previously assigned as cysteamine (2-aminoethanethiol) dioxygenase (ADO), as a high K(m)O(2) N-terminal cysteine dioxygenase that transduces the oxygen-regulated stability of proteins by the N-degron pathw...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Science
Autori principali: Masson, Norma, Keeley, Thomas P., Giuntoli, Beatrice, White, Mark D., Puerta, Mikel Lavilla, Perata, Pierdomenico, Hopkinson, Richard J., Flashman, Emily, Licausi, Francesco, Ratcliffe, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715447/
https://ncbi.nlm.nih.gov/pubmed/31273118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw0112
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi