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Oxidative stress in vagal neurons promotes parkinsonian pathology and intercellular α-synuclein transfer

Specific neuronal populations display high vulnerability to pathological processes in Parkinson’s disease (PD). The dorsal motor nucleus of the vagus nerve (DMnX) is a primary site of pathological α-synuclein deposition and may play a key role in the spreading of α-synuclein lesions within and outsi...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Musgrove, Ruth E., Helwig, Michael, Bae, Eun-Jin, Aboutalebi, Helia, Lee, Seung-Jae, Ulusoy, Ayse, Di Monte, Donato A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715407/
https://ncbi.nlm.nih.gov/pubmed/31194700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127330
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