TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation

The expression of the transmembrane protein 25 gene (Tmem25) is strongly influenced by glutamate ionotropic receptor kainate type subunit 4, and its function remains unknown. Here, we showed that TMEM25 was primarily localized to late endosomes in neurons. Electrophysiological experiments suggested...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Haiqing, Tian, Xin, Lu, Xi, Xu, Demei, Guo, Yi, Dong, Zhifang, Li, Yun, Ma, Yuanlin, Chen, Chengzhi, Yang, Yong, Yang, Min, Yang, Yi, Liu, Feng, Zhou, Ruijiao, He, Miaoqing, Xiao, Fei, Wang, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715386/
https://ncbi.nlm.nih.gov/pubmed/31424425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122599
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