Targeting innate immunity for tuberculosis vaccination

Vaccine development against tuberculosis (TB) is based on the induction of adaptive immune responses endowed with long-term memory against mycobacterial antigens. Memory B and T cells initiate a rapid and robust immune response upon encounter with Mycobacterium tuberculosis, thus achieving long-last...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Khader, Shabaana A., Divangahi, Maziar, Hanekom, Willem, Hill, Philip C., Maeurer, Markus, Makar, Karen W., Mayer-Barber, Katrin D., Mhlanga, Musa M., Nemes, Elisa, Schlesinger, Larry S., van Crevel, Reinout, Vankayalapati, Raman (Krishna), Xavier, Ramnik J., Netea, Mihai G.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715374/
https://ncbi.nlm.nih.gov/pubmed/31478909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128877
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