β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1

β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called “trained immunity,” resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberc...

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發表在:Cell Rep
Main Authors: Moorlag, Simone J.C.F.M., Khan, Nargis, Novakovic, Boris, Kaufmann, Eva, Jansen, Trees, van Crevel, Reinout, Divangahi, Maziar, Netea, Mihai G.
格式: Artigo
語言:Inglês
出版: Cell Press 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242907/
https://ncbi.nlm.nih.gov/pubmed/32433977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107634
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