Fbxw7 increases CCL2/7 in CX3CR1(hi) macrophages to promote intestinal inflammation

Resident and inflammatory mononuclear phagocytes (MPhs) with functional plasticity in the intestine are critically involved in the pathology of inflammatory bowel diseases (IBDs), the mechanism of which remains incompletely understood. In the present study, we found that increased expression of the...

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Pubblicato in:J Clin Invest
Autori principali: He, Jia, Song, Yinjing, Li, Gaopeng, Xiao, Peng, Liu, Yang, Xue, Yue, Cao, Qian, Tu, Xintao, Pan, Ting, Jiang, Zhinong, Cao, Xuetao, Lai, Lihua, Wang, Qingqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715366/
https://ncbi.nlm.nih.gov/pubmed/31246581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123374
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