TGF-β signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond syndrome

Shwachman-Diamond syndrome (SDS) is a rare and clinically heterogeneous bone marrow (BM) failure syndrome caused by mutations in the Shwachman-Bodian-Diamond syndrome (SBDS) gene. Although SDS was described more than 50 years ago, its molecular pathogenesis is poorly understood due, in part, to the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Joyce, Cailin E., Saadatpour, Assieh, Ruiz-Gutierrez, Melisa, Bolukbasi, Ozge Vargel, Jiang, Lan, Thomas, Dolly D., Young, Sarah, Hofmann, Inga, Sieff, Colin A., Myers, Kasiani C., Whangbo, Jennifer, Libermann, Towia A., Nusbaum, Chad, Yuan, Guo-Cheng, Shimamura, Akiko, Novina, Carl D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
Soggetti:
Concise Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715362/
https://ncbi.nlm.nih.gov/pubmed/31211692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125375
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi