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Oxidative stress and α-synuclein conspire in vulnerable neurons to promote Parkinson’s disease progression

Patients with Parkinson’s disease (PD) show selective degeneration of dopaminergic neurons in the substantia nigra and cholinergic neurons in the dorsal motor nucleus (DMnX), but the drivers of this specific susceptibility are unknown. In this issue of the JCI, Musgrove et al. report on their use of...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Hovedforfatter: Luk, Kelvin C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715361/
https://ncbi.nlm.nih.gov/pubmed/31380806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130351
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