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Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson’s Disease

Protein inclusions made up primarily of misfolded α-synuclein (α-Syn) are the hallmark of a set of disorders known as synucleionopathies, most notably Parkinson’s disease (PD). It is becoming increasingly appreciated that α-Syn misfolding can spread to anatomically connected regions in a prion-like...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Luna, Esteban, Luk, Kelvin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679620/
https://ncbi.nlm.nih.gov/pubmed/26505673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.10.023
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