Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib

PURPOSE: Small cell carcinoma of the prostate (SCCP) is an aggressive disease that can arise de novo or by transdifferentiation from prostate adenocarcinoma. Alterations in anaplastic lymphoma kinase (ALK) gene are involved in neuroblastoma, lung cancer, and other malignancies but its role in SCCP h...

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Publicat a:Clin Cancer Res
Autors principals: Carneiro, Benedito A., Pamarthy, Sahithi, Shah, Ami N., Sagar, Vinay, Unno, Kenji, Han, HuiYing, Yang, Ximing J., Costa, Rubens B., Nagy, Rebecca J., Lanman, Richard B., Kuzel, Timothy M., Ross, Jeffrey S., Gay, Laurie, Elvin, Julia A., Ali, Siraj M, Cristofanilli, Massimo, Chae, Young K., Giles, Francis J, Abdulkadir, Sarki A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715284/
https://ncbi.nlm.nih.gov/pubmed/29559559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0332
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