Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib

PURPOSE: Small cell carcinoma of the prostate (SCCP) is an aggressive disease that can arise de novo or by transdifferentiation from prostate adenocarcinoma. Alterations in anaplastic lymphoma kinase (ALK) gene are involved in neuroblastoma, lung cancer, and other malignancies but its role in SCCP h...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Carneiro, Benedito A., Pamarthy, Sahithi, Shah, Ami N., Sagar, Vinay, Unno, Kenji, Han, HuiYing, Yang, Ximing J., Costa, Rubens B., Nagy, Rebecca J., Lanman, Richard B., Kuzel, Timothy M., Ross, Jeffrey S., Gay, Laurie, Elvin, Julia A., Ali, Siraj M, Cristofanilli, Massimo, Chae, Young K., Giles, Francis J, Abdulkadir, Sarki A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715284/
https://ncbi.nlm.nih.gov/pubmed/29559559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0332
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