Pharmacological Differentiation of Thrombomodulin Alfa and Activated Protein C on Coagulation and Fibrinolysis In Vitro

Although thrombomodulin alfa (TM alfa), recombinant human soluble thrombomodulin, exerts antithrombogenic effects through activated protein C (APC), clinical trials suggested that TM alfa has a lower bleeding risk than does recombinant human APC. To address the mechanism explaining this difference,...

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Bibliografische gegevens
Gepubliceerd in:Clin Appl Thromb Hemost
Hoofdauteurs: Tanaka, Kosuke, Tawara, Shunsuke, Tsuruta, Kazuhisa, Hoppensteadt, Debra, Fareed, Jawed
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2018
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714727/
https://ncbi.nlm.nih.gov/pubmed/29683037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029618770274
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