Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon

Thrombin activatable fibrinolysis inhibitor (TAFI), when activated, forms a basic carboxypeptidase that can inhibit fibrinolysis. Potential physiologic activators include both thrombin and plasmin. In vitro, thrombomodulin and glycosaminoglycans increase the catalytic efficiency of TAFI activation b...

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Detalhes bibliográficos
Main Authors: Binette, Tanya M., Taylor, Fletcher B., Peer, Glenn, Bajzar, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200911/
https://ncbi.nlm.nih.gov/pubmed/17644733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-078824
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