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Polycystin‐1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines

Polycystic Kidney Disease (PKD), which is attributable to mutations in the PKD1 and PKD2 genes encoding polycystin‐1 (PC1) and polycystin‐2 (PC2) respectively, shares common cellular defects with cancer, such as uncontrolled cell proliferation, abnormal differentiation and increased apoptosis. Inter...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Papavassiliou, Kostas A., Zoi, Ilianna, Gargalionis, Antonios N., Koutsilieris, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714176/
https://ncbi.nlm.nih.gov/pubmed/31251475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14506
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