Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study

BACKGROUND: Hereditary angioedema (HAE) is a debilitating disorder resulting from C1-esterase inhibitor (C1-INH) deficiency. In the COMPACT phase 3 study the prophylactic use of a subcutaneous C1 inhibitor (C1-INH [SC], HAEGARDA(®), CSL Behring) twice weekly significantly reduced the frequency of ac...

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Detalles Bibliográficos
Publicado en:Allergy Asthma Clin Immunol
Main Authors: Li, H. Henry, Zuraw, Bruce, Longhurst, Hilary J., Cicardi, Marco, Bork, Konrad, Baker, James, Lumry, William, Bernstein, Jonathan, Manning, Michael, Levy, Donald, Riedl, Marc A., Feuersenger, Henrike, Prusty, Subhransu, Pragst, Ingo, Machnig, Thomas, Craig, Timothy
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714075/
https://ncbi.nlm.nih.gov/pubmed/31485239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-019-0362-1
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