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Na-K-2Cl Cotransporter and Store-Operated Ca(2+) Entry in Pacemaking by Interstitial Cells of Cajal

Pacemaker depolarization in interstitial cells of Cajal (ICCs) is believed to be induced by Ca(2+) transients and activation of anoctamin-1 (Ano1) channels in the plasma membrane. However, block of store-operated calcium entry (SOCE) or the Na-K-2Cl cotransporter (NKCC1) terminates pacemaker activit...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Youm, Jae Boum, Zheng, Haifeng, Koh, Sang Don, Sanders, Kenton M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713646/
https://ncbi.nlm.nih.gov/pubmed/31400920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.020
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