Hepatitis B virus X protein enhances hepatocarcinogenesis by depressing the targeting of NUSAP1 mRNA by miR-18b

OBJECTIVE: The aim of this study was to investigate the underlying mechanism whereby HBx modulates the targeting of NUSAP1 by miR-18b to enhance hepatocarcinogenesis. METHODS: We employed an integrated approach of bioinformatics analysis and molecular experiments in hepatoma cells, HBV transgenic mi...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Yang, Zhe, Li, Jiong, Feng, Guoxing, Wang, Yuan, Yang, Guang, Liu, Yunxia, Zhang, Shuqin, Feng, Jinyan, Zhang, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713641/
https://ncbi.nlm.nih.gov/pubmed/31516748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0283
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