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MicroRNA-145 Modulates N(6)-Methyladenosine Levels by Targeting the 3′-Untranslated mRNA Region of the N(6)-Methyladenosine Binding YTH Domain Family 2 Protein
N(6)-Methyladenosine (m(6)A) is a prevalent modification present in the mRNAs of higher eukaryotes. YTH domain family 2 (YTHDF2), an m(6)A “reader” protein, can recognize mRNA m(6)A sites to mediate mRNA degradation. However, the regulatory mechanism of YTHDF2 is poorly understood. To this end, we i...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339747/ https://ncbi.nlm.nih.gov/pubmed/28104805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749689 |
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