Effects of palbociclib on oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

OBJECTIVE: Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including amplification of cyclin D1 and loss of p16. Hence...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Zainal, Nur Syafinaz, Lee, Bernard Kok Bang, Wong, Zheng Wei, Chin, Iuan Sheau, Yee, Pei San, Gan, Chai Phei, Mun, Kein Seong, Rahman, Zainal Ariff Abdul, Gutkind, J. Silvio, Patel, Vyomesh, Cheong, Sok Ching
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713638/
https://ncbi.nlm.nih.gov/pubmed/31516747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0257
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