Effects of palbociclib on oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

OBJECTIVE: Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including amplification of cyclin D1 and loss of p16. Hence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Biol Med
Egile Nagusiak: Zainal, Nur Syafinaz, Lee, Bernard Kok Bang, Wong, Zheng Wei, Chin, Iuan Sheau, Yee, Pei San, Gan, Chai Phei, Mun, Kein Seong, Rahman, Zainal Ariff Abdul, Gutkind, J. Silvio, Patel, Vyomesh, Cheong, Sok Ching
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Chinese Anti-Cancer Association 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713638/
https://ncbi.nlm.nih.gov/pubmed/31516747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0257
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