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Label-Free Pathogen Detection by a Deoxyribozyme Cascade with Visual Signal Readout

A colorimetric nucleic acid based test for label-free pathogen detection has been developed and used for the detection of the Zika virus. The test relies on nucleic acid sequence-based amplification (NASBA) of a viral RNA followed by interrogation of the amplicon by a cascade of deoxyribozymes const...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sens Actuators B Chem
Hauptverfasser: Reed, Adam J., Connelly, Ryan P., Williams, Allison, Tran, Maithi, Shim, Byoung-Shik, Choe, Hyeryun, Gerasimova, Yulia V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713451/
https://ncbi.nlm.nih.gov/pubmed/31462856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.snb.2018.11.147
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