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Interrogation of highly structured RNA with multicomponent deoxyribozyme probes at ambient temperatures

Molecular analysis of RNA through hybridization with sequence-specific probes is challenging due to the intrinsic ability of RNA molecules to form stable secondary and tertiary structures. To overcome the energy barrier toward the probe–RNA complex formation, the probes are made of artificial nucleo...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Reed, Adam J., Sapia, Ryan J., Dowis, Charles, Solarez, Sheila, Gerasimova, Yulia V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668264/
https://ncbi.nlm.nih.gov/pubmed/32859694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.074864.120
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