Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans

OBJECTIVE: Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and its relation to coronary heart disease (CHD) ha...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: van Keulen, Danielle, Pouwer, Marianne G., Emilsson, Valur, Matic, Ljubica Perisic, Pieterman, Elsbet J., Hedin, Ulf, Gudnason, Vilmundur, Jennings, Lori L., Holmstrøm, Kim, Nielsen, Boye Schnack, Pasterkamp, Gerard, Lindeman, Jan H. N., van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713386/
https://ncbi.nlm.nih.gov/pubmed/31461490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221477
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