Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans

OBJECTIVE: Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and its relation to coronary heart disease (CHD) ha...

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Pubblicato in:PLoS One
Autori principali: van Keulen, Danielle, Pouwer, Marianne G., Emilsson, Valur, Matic, Ljubica Perisic, Pieterman, Elsbet J., Hedin, Ulf, Gudnason, Vilmundur, Jennings, Lori L., Holmstrøm, Kim, Nielsen, Boye Schnack, Pasterkamp, Gerard, Lindeman, Jan H. N., van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713386/
https://ncbi.nlm.nih.gov/pubmed/31461490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221477
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