High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias

Autoimmune cytopenias (AIC) such as immune thrombocytopenia or autoimmune hemolytic anemia are claimed to be essentially driven by a dysregulated immune system. Using next-generation immunosequencing we profiled 59 T and B cell repertoires (TRB and IGH) of 25 newly diagnosed patients with primary or...

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Vydáno v:Front Immunol
Hlavní autoři: Simnica, Donjete, Schliffke, Simon, Schultheiß, Christoph, Bonzanni, Nicola, Fanchi, Lorenzo F., Akyüz, Nuray, Gösch, Barbara, Casar, Christian, Thiele, Benjamin, Schlüter, Janina, Lohse, Ansgar W., Binder, Mascha
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713037/
https://ncbi.nlm.nih.gov/pubmed/31497012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01897
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