Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection

Viral infections are a common cause of asthma exacerbations, with human rhinoviruses (RV) the most common trigger. RV signals through a number of different receptors, including toll-like receptor (TLR)3. Tenascin-C (TN-C) is an immunomodulatory extracellular matrix protein present in high quantities...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mills, Jake T., Schwenzer, Anja, Marsh, Elizabeth K., Edwards, Michael R., Sabroe, Ian, Midwood, Kim S., Parker, Lisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712508/
https://ncbi.nlm.nih.gov/pubmed/31497021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01987
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