Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K‐Akt signaling in gastric cancer

BACKGROUND: As the most abundant epigenetic modification on mRNAs and long non‐coding RNAs, N6‐methyladenosine (m6A) modification extensively exists in mammalian cells. Controlled by writers (methyltransferases), readers (signal transducers), and erasers (demethylases), m6A influences mRNA structure...

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Bibliografski detalji
Izdano u:Cancer Med
Glavni autori: Zhang, Cheng, Zhang, Mengqi, Ge, Sai, Huang, Wenwen, Lin, Xiaoting, Gao, Jing, Gong, Jifang, Shen, Lin
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Cancer Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712480/
https://ncbi.nlm.nih.gov/pubmed/31243897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2360
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