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Proteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast

The 26S proteasome conducts the majority of regulated protein catabolism in eukaryotes. At the heart of the proteasome is the barrel-shaped 20S core particle (CP), which contains two β-rings sandwiched between two α-rings. Whereas canonical CPs contain α-rings with seven subunits arranged α1-α7, a n...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Howell, Lauren A., Peterson, Anna K., Tomko, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712033/
https://ncbi.nlm.nih.gov/pubmed/31455793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48889-5
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