Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

Blockade of the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction has emerged as a powerful strategy in cancer immunotherapy. Recently, there have been enormous efforts to develop potent PD-1/PD-L1 inhibitors. In particular, Bristol-Myers Squibb (BMS) and Aurigene Dis...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ganesan, Aravindhan, Ahmed, Marawan, Okoye, Isobel, Arutyunova, Elena, Babu, Dinesh, Turnbull, William L., Kundu, Joydeb Kumar, Shields, Justin, Agopsowicz, Katharine Cheryl, Xu, Lai, Tabana, Yasser, Srivastava, Nutan, Zhang, Guangzhi, Moon, Tae Chul, Belovodskiy, Alexandr, Hena, Mostofa, Kandadai, Appan Srinivas, Hosseini, Seyedeh Nargess, Hitt, Mary, Walker, John, Smylie, Michael, West, Frederick G., Siraki, Arno G., Lemieux, M. Joanne, Elahi, Shokrollah, Nieman, James A., Tyrrell, D. Lorne, Houghton, Michael, Barakat, Khaled
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712002/
https://ncbi.nlm.nih.gov/pubmed/31455818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48826-6
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